Duties Manage a new laboratory and provision of related facilities including operation and maintenance of the laboratory, procurement of laboratory equipment and regents; manage inventory of laboratory equipment and items; maintain and operate all shared laboratory facilities; establish and maintain laboratory standard operating procedures; and assist in the R&D projects where required. Requirements Applicants should have a bachelor’s degree in science and/or engineering disciplines, at least 6 years’ relevant experience; knowledge in neuroscience, stem cell culture and genomics will be an asset. A team player with a strong sense of responsibility, independent, good interpersonal and problem-solving skills; knowledge in laboratory management, laboratory building services, electrical and mechanical services is preferable; knowledge of principles, practices, and procedures of laboratory testing; ability to operate standard laboratory testing equipment; knowledge of safe laboratory practices, laboratory safety equipment and safety management; and competent in MS Office. Salary and Benefits Salary will be commensurate with qualification and experience. Medical and dental benefits as well as annual leave will be provided. Appointment will be offered on a contract basis, renewable subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

We are seeking a motivated individual to join our team in developing workflows and toolsets for various cores in Center. This is an excellent opportunity to immerse oneself into an inter-disciplinary field that brings together technology with biology. Duties The appointee will take part in various research projects within the Center by providing technical support, and is expected to keep pace with technological advancement and provide technical assistance in the following areas: Proteomics Molecular biology Bioinformatics Research data analysis Clinical data organization Assay development Requirements A bachelor degree or higher degree in related disciplines Possess extensive hands-on experience in the area(s) above With strong analytical, communication and interpersonal skills Be able to communicate effectively in English Salary and Benefits A highly competitive salary will be commensurate with qualification and experience in addition to medical and dental benefits as well as annual leave. The appointment will be offered on a contract basis, renewable subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

Duties The appointee will assist the Management in the administration of R&D projects with duties including: Compiling research proposals Ensuring the research progress meeting the project plans Preparing reports for research projects Conducting literature search and IP applications Coordinating and liaising with internal and external parties on project administration activities Providing daily administrative support to related tasks Performing any other duties as assigned Requirements PhD or Master’s degree in Life Science or a related field Preferably with at least 5 years’ relevant working experience Self-motivated, able to work independently and also work well in a team Excellent command of both spoken and written English and Chinese Fluency in Putonghua would be advantageous Proficiency in all MS Office Experience in the administration of Government funded R&D projects is highly desirable Ability to meet deadlines Salary and Benefits A highly competitive salary will be commensurate with qualification and experience in addition to medical and dental benefits as well as annual leave. The appointment will be offered on a contract basis, renewable subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

Hong Kong Center for Neurodegenerative Diseases (HKCeND) is an interdisciplinary research institute that aims to carry out cutting-edge high-impact molecular neuroscience, genetic and clinical research in characterizing the mechanistic underpinnings of Alzheimer’s disease and dementia in the Chinese population. We are looking for highly motivated Research Assistant(s)/Associate(s) to join our Drug Discovery team. The candidate(s) will actively participate in and contribute to the research and development of novel strategies for drug discovery. The appointee will assist in the generation of reporter cell lines, Antisense Oligonucleotide (ASO) screening, and genome editing. Training will be provided as needed in laboratory techniques, which include cell culture, genome editing, establishment of reporter cell lines and immunoassays. Duties Small- and large-scale tissue culture. Perform various cell treatments and drug screening in cell lines. Perform genome editing and generate reporter cell lines. Perform phenotyping assays including western blotting, qRT-PCR, ELISA, luciferase assays etc. Undertake any necessary training as required, to attain and provide technical expertise. Maintain complete and accurate records of the experimental data and analyses performed. Present and discuss research progress and results within the team. Perform general project administrative tasks, such as maintaining general upkeep, equipment and stocks of supplies for research use. Support the preparation of technical reports and quantitative analyses   We Offer You On-the-job training. Mentoring and training as part of an active research environment at HKCeND and HKUST. Professional development with career opportunities and training within a collaborative and interdisciplinary environment.   Requirements For Research Assistant: Bachelor’s degree in Biology / Molecular Biology / Biochemistry / Biomedical Sciences or related field. Experience in cell culture and molecular biology-related laboratory techniques preferred. Self-motivated, detail-oriented, team-oriented, with the ability to work independently. Ability to follow oral and written instructions and to perform tasks with minimal supervision. Outstanding communication and interpersonal skills.   For Research Associate: PhD in Biology / Biochemistry / Molecular Biology / Biomedical Sciences or related field. Research experience in biochemistry, drug discovery and development is a plus. Strong passion and commitment to science. Strong interpersonal and organizational skills, and the ability to thrive in a fast-paced dynamic environment. Ability to plan and perform drug screening experiments and analyse/interpret data.   Salary and Benefits A highly competitive salary will be commensurate with qualification and experience in addition to medical and dental benefits as well as annual leave. The appointment will be offered a renewable one-year contract, subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

We are looking for highly motivated Research Assistant(s) to join our Histology team. The candidate(s) will contribute to the collective efforts directed at the roles of biomarkers underlying the dysregulation of Alzheimer’s Disease (AD), contributing to disease pathogenesis with stepwise histopathological progression. The recent projects are focused on human AD neuropathological hallmarks, microscopically hint on the intricate molecular interplay of signalling pathways through observations of neuropathological abnormalities from various brain banks’ post-mortem human brain samples. The ideal candidate(s) will gain exposure to hands-on translational research, with the primary focus on neuropathological alternations at the cutting-edge microscopic level. He/She will mainly be responsible to work with mouse whole/half-brain samples and the precious post-mortem human brain samples, through conducting immunostaining with a wide array of molecular markers, followed by 2D and/or 3D bioimage analysis, to examine microanatomical lesions to support research projects of relevance. Duties Processing, staining (IHC, IF), imaging and basic interpretations of the tissue images. Implement and/or optimize existing protocols and bioimage analysis pipelines with documentation. Undertake any necessary training as required, to provide technical expertise. Maintain good records of the experimental data and analyses performed. Performing general project administrative tasks, such as maintaining general upkeep, equipment and stocks of supplies needed for research. Support the preparation of manuscripts and presentations, where applicable.   We Offer You On-the-job training in immunostaining, (multiplexed) widefield and confocal imaging of tissue specimens from post-mortem human brain and mice model(s), also respective customized bioimage analysis pipelines. Mentoring and training as part of an active research environment in HKCeND and HKUST. Professional development with career opportunities and training within collaborative and interdisciplinary environment.   Requirements Bachelor’s degree in Bio-(medical) engineering and Life Sciences, including Biology / Biochemistry / Molecular Biology / Biomedical Sciences/Bioinformatics/Computational Biology or related field. A creative mind who are curious and willing to learn new techniques and software as necessary. Strong written and verbal communication skills in English. Self-motivated, detail-oriented, team-oriented with the ability to work proactively. Excellent interpersonal, organizational skills and able to prioritise own work in response to deadlines.   Desirable Candidate Self-driven learner who are keen to develop new skillsets and learn about computational image analyses, come join us to develop and further optimise analytical tools for massive bioimages. Think tank for model-based image processing and analysis algorithms on top of existing ones. Experience of tissue handling and histology, with basic laboratory skills in molecular biology and neuroscience (genotyping, immunostaining, microscopy, etc.). Basic statistical knowledge and skills, including familiarity with statistical analysis software such as GraphPad Prism, R or SPSS. Basic programming concepts and/or skills such as Python, MATLAB or Java will be an advantage. Data management experience with relational database architecture is a plus but not necessary.   Salary and Benefits A highly competitive salary will be commensurate with qualification and experience in addition to medical and dental benefits as well as annual leave. The appointment will be offered a renewable one-year contract, subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

We are seeking for a highly energetic and motivated Research Assistant to join our Machine learning team at Hong Kong Center for Neurodegenerative Diseases, based at the Hong Kong Science Park. The ideal candidate will have the opportunity to actively participate and contribute to the research and development of novel strategies for high-throughput imaging-based drug discovery. The appointee will support various research projects by conducting computational analyses. This is an excellent opportunity to immerse oneself into an inter-disciplinary field that brings together information technology with biology. Duties Collect, manage, and study biological data (microscopy images and/or NGS data), including the use of machine learning and statistical methods to analyse and interpret data for meaningful results. Implement and/or optimize existing analysis pipelines with inputs from biologists and deliver the insights of the data responsibly and timely. Maintain good records of the data and analyses performed.   Requirements Bachelor’s degree in computer science or a related field. Interest in the field of life sciences would be beneficial but prior knowledge in this area is not required. Strong programming skills, especially with Python. Knowledge of R is a plus. Ability to implement computer vision algorithms using popular deep learning frameworks such as Pytorch, Tensorflow, and standard libraries such as OpenCV. Strong analytical, communication and interpersonal skills with ability to communicate effectively in English. Curiosity and the professional skillset to excel in an open, highly collaborative and multidisciplinary environment. Good organizational skills with an appreciation of software engineering practices and the ability to work independently are required. Familiarity with the administration of Linux and HPC systems including troubleshooting software installation, deployment, and execution would be an asset. Knowledge of relational database architecture such as MySQL and PostgreSQL is a plus.   Salary and Benefits A highly competitive salary will be commensurate with qualification and experience in addition to medical and dental benefits as well as annual leave. The appointment will be offered a renewable one-year contract, subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

We are seeking for a highly energetic and motivated Research Assistant to join our Cell Biology team at Hong Kong Center for Neurodegenerative Diseases, based at the Hong Kong Science Park. The ideal candidate will have the opportunity to actively participate and contribute to the research and development of novel strategies for high-throughput imaging-based drug discovery. The appointee will assist in research in the area of biologic drug development. Training will be provided as needed in laboratory techniques such as that involves in vitro cell culture, protein separation, purification, and identification using cutting-edge technologies. Duties Small- and large-scale tissue culture. Perform various cell treatments such as virus-mediated gene expression. Perform phenotyping assays including western blot, RT-qPCR, etc. Handling of large volumes of conditioned media for preparation of biologics libraries. Implement and optimize protocols for protein separation and purification using liquid chromatography techniques. Sample preparation for protein identification using mass-spectrometry. Maintain complete and accurate records, laboratory documentation and electronic files. Present and discuss results of experiments within the project team. Collaboration with other multidisciplinary teams to achieve common goals. Lab maintenance, i.e. ordering supplies, general upkeep, etc. Preparation of technical reports, summaries and quantitative analysis.   Requirements Bachelor’s degree in Biology/Molecular Biology/Biochemistry/Biomedical Sciences or related field. Willing to work hours during weekdays and weekends depending on experimental needs. Strong interpersonal and organizational skills and the ability to thrive in a fast-paced dynamic environment. Self-motivated, detail-oriented, team-oriented with the ability to work independently. Ability to follow oral and written instructions and to perform tasks with minimal supervision. Experience in cell biology- and molecular biology-based laboratory techniques is preferred.   Salary and Benefits A highly competitive salary will be commensurate with qualification and experience in addition to medical and dental benefits as well as annual leave. The appointment will be offered a renewable one-year contract, subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

We are seeking for highly energetic and motivated Research Assistants to join our Cell Biology team at Hong Kong Center for Neurodegenerative Diseases, based at the Hong Kong Science Park. The ideal candidate(s) will have the opportunity to actively participate and contribute to the research and development of novel strategies for high-throughput imaging-based drug discovery. Training will be provided as needed in laboratory techniques such as in vitro cell culture, performing cell treatments, immunostaining, and microscopy imaging using cutting-edge technologies. Duties Small- and large-scale tissue culture. Perform various cell treatments such as stimulation with growth factors/cytokines, siRNA-mediated gene silencing, gene overexpression studies, etc. Perform phenotyping assays such as western blot, RT-qPCR, etc. Implement and optimize protocols for immunostaining with multiple antibodies. Confocal and live cell imaging microscopy. Maintain complete and accurate records, laboratory documentation and electronic files. Present and discuss project progress at regular team meetings. Collaborate with other multidisciplinary teams to achieve common goals. Laboratory maintenance, i.e. ordering laboratory supplies, performing general upkeep, etc. Preparation of technical reports, summaries and quantitative analysis of data.   Requirements Bachelor’s degree in Biology/Molecular Biology/Biochemistry/Biomedical Sciences or related field. Willing to work hours during weekdays and weekends depending on experimental needs. Strong interpersonal and organizational skills and the ability to thrive in a fast-paced dynamic environment. Self-motivated, detail-oriented, team-oriented with the ability to work independently. Ability to follow oral and written instructions and to perform tasks with minimal supervision. Experience in cell biology- and molecular biology-based laboratory techniques is preferred.   Salary and Benefits A highly competitive salary will be commensurate with qualification and experience in addition to medical and dental benefits as well as annual leave. The appointment will be offered a renewable one-year contract, subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

Duties Mainly deployed on clinical and non-clinical duties in the areas including providing medical consultation, counselling and health education to study subjects in research programme related to aging and memory loss Successful candidates may work in the mornings on weekdays; need to work at Hong Kong Science Park   Requirements A medical qualification registrable in Hong Kong under the Medical Registration Ordinance, Cap. 161; A good command of spoken and written Chinese and English; and Be able to speak fluent Cantonese.   Salary and Benefits HK$600 - HK$800 per hour depending on relevant experience. The appointment will be offered a one-year contract, renewable subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

Duties Responsible for blood drawing, sample collection Requirements Form 5 or above Recognized phlebotomist certificate Relevant working experience is preferable Familiar with basic computer operation 5 days working (Full time); 2-3 days working (Part Time); Sunday and Public Holidays off   Salary and Benefits A highly competitive salary will be commensurate with qualification and experience in addition to medical and dental benefits as well as annual leave. The appointment will be offered on a one-year contract basis, renewable subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

We are seeking a motivated individual to join our team in developing workflows and toolsets for various cores in the Center. This is an excellent opportunity to immerse oneself into an inter-disciplinary field that brings together technology with biology. Duties Oversee the day-to-day operation of laboratory facility with a wide range of sophisticated scientific instruments/platforms, such as mass spectrometry, liquid chromatography, confocal microscopy, next-generation sequencing, cell sorting, automated single-cell imaging and picking system, automated quantitative multiplex imaging system, automated digital immunoassay Develop standard operation procedures and training sessions for lab users Assist in purchase, inventory and maintenance of instrument/platforms Perform other tasks assigned by supervisors Requirements A bachelor’s degree or higher degree in biological sciences or related disciplines Experience in working in life science core facility or hands-on experience in the area(s) above With strong analytical, communication and interpersonal skills Highly motivated and fast learning Be able to communicate effectively in Cantonese, English and Mandarin Salary and Benefits A highly competitive salary will be commensurate with qualification and experience in addition to medical and dental benefits as well as annual leave. The appointment will be offered on a contract basis, renewable subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

The appointee will support various research projects by conducting computational analyses. This is an excellent opportunity to immerse oneself into an inter-disciplinary field that brings together information technology with biology. Duties Analyze data sets using existing open-source tools Develop and deploy custom-made scripts or programs that integrate with other tools Maintain good records of the analyses performed Attend project meetings as needed Requirements Bachelor’s degree in computer science or a related field. Interest in the field of life sciences would be beneficial but prior knowledge in this area is not required Knowledge of Linux-based systems and shell scripting, with additional programming skills including Perl, Python, and R Good organizational skills with an appreciation of software engineering practices and the ability to work independently are required Familiarity with the administration of Linux systems including troubleshooting software installation, deployment, and execution would be an asset Strong analytical, communication and interpersonal skills and be able to communicate effectively in English Salary and Benefits A highly competitive salary will be commensurate with qualification and experience in addition to medical and dental benefits as well as annual leave. The appointment will be offered a one-year contract, renewable subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

Duties The appointees will participate in a molecular neuroscience-related, and/or genetic-based research program(s). Requirements Applicants should have a bachelor’s degree in biological sciences or a related field with solid and substantial work experience; a master’s degree in an advantage. Knowledge on molecular biology, cell biology and biochemistry is necessary. Relevant working experience in clinical or hospital settings, biological sample processing, patient recruitment, or translational science is an asset. Self-motivation with the ability to work independently is essential. Salary and Benefits Salary will be commensurate with qualification and experience. Medical and dental benefits as well as annual leave will be provided. Appointment will be offered on a contract basis, renewable subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

Duties Successful candidates will study the roles and the effect of genetic risk factors in neurodegenerative diseases through a systems approach, involving epigenetic, transcriptomic, and proteomics analysis. They will also be required to process and analyze human tissues, including frozen brain tissues and paraffin blocks. The positions provide exchange opportunities and the successful candidates will work closely with renowned laboratories at international institutions. Requirements Applicants should have a PhD degree in life science; background in neuroscience, neuroanatomy or a related field; and research experience in human tissues, histology and immunohistology. Knowledge of neuro-pathology, genomic DNA, RNA, and biochemistry techniques is preferred. The appointee should possess outstanding communication skills and strong passion and commitment to science, and enjoy working in a multidisciplinary and diverse team. Salary and Benefits Salary will be commensurate with qualification and experience. Medical and dental benefits as well as annual leave will be provided. Appointment will be offered on a contract basis, renewable subject to mutual agreement and performance. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.

Duties We are seeking highly motivated and organized applicants to join our team. The Senior Scientist / Scientist positions will facilitate the development and execution of novel scientific strategies at our state-of-the-art laboratory. The successful applicants will be responsible for overseeing the administration of neuroscience research programs, management of financial and human resources, sponsor and volunteer relations, and external communications. Requirements For the Scientist positions, the ideal candidate has a Ph.D. degree in life sciences or a related field, with a minimum of three years of hands-on experience working in a research setting. Experience in the area of neuroscience is an asset but not necessary. For the Senior Scientist position, a minimum of five years of managerial experience is required. Relevant experience in standard molecular biology and neuroscience-related techniques is a must. Technical writing experience is required. This position is ideal for an individual who can work independently in a thriving complex environment with exceptional interpersonal and communication skills. Salary and Benefits A highly competitive salary will be commensurate with qualification and experience in addition to medical and dental benefits as well as annual leave. The appointment will be offered a two-year contract, renewable subject to mutual agreement and performance. A gratuity will be payable upon successful completion of contract. Application Procedure Applicants should submit their up-to-date CV and cover letter with salary expectation and availability. We thank applicants for their interest, but advise that only shortlisted candidates will be notified of the results of their applications. Review of applications will commence shortly and continue until the position is filled. The information provided will be kept confidential and be used for recruitment and other employment-related purposes. We are an equal opportunity employer and welcome applications from all qualified candidates.